Drug Name

Grisovin FP (griseofulvin)

Drug Uses

Grisovin FP is an antifungal medication. It is like an antibiotic but is used to treat fungal infections.

Grisovin FP may also be used for purposes other than those listed in this medication guide.

How to use

Take griseofulvin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass (8 ounces) of water. Your doctor may recommend that you take griseofulvin with a fatty meal to increase its absorption into your body. Take all of the griseofulvin that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.

Griseofulvin Dosing Information
Usual Adult Dose for Onychomycosis -- Fingernail:
Microsize formulation: 1000 mg/day orally in 2 to 4 divided doses
Ultramicrosize formulation: 660 to 750 mg/day orally in 2 to 4 divided doses

Usual Adult Dose for Onychomycosis -- Toenail:
Microsize formulation: 1000 mg/day orally in 2 to 4 divided doses
Ultramicrosize formulation: 660 to 750 mg/day orally in 2 to 4 divided doses

Usual Adult Dose for Tinea Pedis:
Microsize formulation: 1000 mg/day orally in 2 to 4 divided doses
Ultramicrosize formulation: 660 to 750 mg/day orally in 2 to 4 divided doses

Usual Adult Dose for Tinea Barbae:
Microsize formulation: 500 mg/day orally in single or 2 divided doses
Ultramicrosize formulation: 330 to 375 mg/day orally in single or divided doses

Usual Adult Dose for Tinea Capitis:
Microsize formulation: 500 mg/day orally in single or 2 divided doses
Ultramicrosize formulation: 330 to 375 mg/day orally in single or divided doses

Usual Adult Dose for Tinea Corporis:
Microsize formulation: 500 mg/day orally in single or 2 divided doses
Ultramicrosize formulation: 330 to 375 mg/day orally in single or divided doses

Usual Adult Dose for Tinea Cruris:
Microsize formulation: 500 mg/day orally in single or 2 divided doses
Ultramicrosize formulation: 330 to 375 mg/day orally in single or divided doses

Drug Class and Mechanism

Griseofulvin is an antifungal medication. It is like an antibiotic but is used to treat fungal infections.

Missed Dose

Take the missed dose as soon as you remember. Take the rest of the day's doses at evenly spaced intervals unless your doctor directs otherwise.

Storage

Store griseofulvin tablets, capsules, and suspension at room temperature away from moisture and heat.

Warnings/Precautions

You cannot take griseofulvin if you

• have ever had an allergic reaction to it,
• have porphyria, or
• have liver disease.

Talk to your doctor before taking griseofulvin if you have any of the conditions listed above.
Griseofulvin is in the FDA pregnancy category C. This means that it is not known whether griseofulvin will harm an unborn baby. In rare cases, the use of griseofulvin has been associated with conjoined twins. Do not take this medication without first talking to your doctor if you are pregnant. It is also not known whether griseofulvin passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. Griseofulvin may affect sperm and sperm production. It is recommended that you avoid fathering a child during treatment with griseofulvin and for 6 months following therapy.

Possible Side Effects

Stop taking griseofulvin and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).
Other, less serious side effects may be more likely to occur. Continue to take griseofulvin and notify your doctor if you experience

• white patches in your mouth (thrush/yeast infection);
• nausea, vomiting, or diarrhea;
• headache, dizziness, or tiredness;
• insomnia;
• confusion;
• numbness or tingling in your hands or feet; or
• menstrual irregularities.

More Information

Your pharmacist can provide more information about griseofulvin.